Is your ELIGARD® correctly prepared? If not, go back to Step: Preparation
Follow the step-by-step instructions below, or watch the full mixing & administration training video.
Pull out (do NOT unscrew) the short blue plunger rod with attached gray stopper from Syringe B. Discard both the blue plunger and attached gray stopper.
Gently screw the white plunger rod into the remaining gray stopper in Syringe B.
Unscrew and discard the clear cap from Syringe A. Remove and discard the gray rubber cap from Syringe B.
Join the two syringes together by pushing and gently screwing until secure.
Inject the liquid contents of Syringe A into the leuprolide acetate powder of Syringe B.
Mix the product for 45 seconds by pushing the contents back and forth between both syringes to obtain a uniform suspension (This is a great time to set expectations for the injection with the patient).
When thoroughly mixed, the suspension will appear light tan to tan (ELIGARD® 7.5 mg) or colorless to pale yellow (ELIGARD 22.5 mg, 30 mg and 45 mg).
Note: Product must be mixed as described; shaking will NOT provide adequate mixing.
After mixing, hold the syringes vertically (upright) with Syringe B (short, wide syringe) on the bottom. The syringes should remain securely coupled.
Draw all of the mixed product into Syringe B by depressing the Syringe A plunger and slightly withdrawing the Syringe B plunger.
Unscrew Syringe A to decouple the syringes while continuing to push down on the Syringe A plunger.
Note: Do not attempt to remove small air bubbles that remain in the formulation – this is acceptable for subcutaneous injections.
Continue to hold Syringe B upright with the open end at the top.
Hold back the white plunger on Syringe B to prevent loss of the product and attach the safety needle cartridge. Gently screw clockwise with approximately a three-quarter turn until the needle is secure.
Do not overtighten, as the hub may become damaged resulting in leakage of the product during injection. The safety sheath may also be damaged if the needle is screwed with too much force.
Move the safety sheath away from the needle and towards the syringe and pull off the clear needle cartridge cover immediately prior to administration.
Note: Should the needle hub appear to be damaged, or leak, ELIGARD should NOT be used. The damaged needle should NOT be replaced and the product should NOT be injected.