Dosage forms & strengths
ELIGARD provides flexible dosing options with technology that enables small injection volumes. 
The injection delivers the dose of leuprolide acetate incorporated in a polymer formulation.
|Injection Volume||0.25 mL||0.375 mL||0.50 mL||0.375 mL|
|Mean serum testosterone|
level at study conclusion*
|6.1 ng/dL||10.1 ng/dL||12.4 ng/dL||12.6 ng/dL|
|Mean PSA reduction||94%||98%||86%||97%|
ELIGARD® is an injectable suspension of leuprolide acetate available in a single- dose kit. The kit consists of two prefilled syringes whose contents are mixed immediately prior to administration.
The syringes are packaged separately: Syringe A contains the in-situ polymeric gel extended Delivery System and the Syringe B contains leuprolide acetate powder. The two syringes are joined and the single dose product is mixed until it is homogenous.  When reconstituted, ELIGARD is administered as a single dose.
The kit also contains a sterile safety needle (Table 1), a desiccant, and a package insert for reconstitution and administration procedures.
|7.5 mg (1 injection every month)||20-gauge||5/8-inch|
|22.5 mg (1 injection every 3-months)||20-gauge||5/8-inch|
|30 mg (1 injection every 4-months)||20-gauge||5/8-inch|
|45 mg (1 injection every 6-months)||18-gauge||5/8-inch|
See Mixing & Administration for full details.
- ELIGARD® (leuprolide acetate) for injectable suspension 7.5 mg, 22.5 mg, 30 mg, 45 mg prescribing information. Fort Collins, CO: Tolmar Therapeutics, Inc.; 2019.